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9PTmAm2ORJ-2Fb7C-2B6empSJP3S5WNEmfu8d-2FxLPeXZI0N3l4-2FkTXeF1QEkdEwR7Sl1Uns=
-2B4XQywhGhd1QxgZTMQlXi30kaZZmUgeXR0jEKDGo_xDPID0vOuylFAU8fv4e60wei4JxqEGBd=
VWu7KiDwjI3b8sYN46DL86bSl0KxvPs6EFaZqddW-2FBZlGB52Zlf-2FOeoCOG9ekocVj-2F2X9=
c9g1wYOvrtM6DlJeULeIaUcHdhgXOVk1wLTP3tkYficVDrAo3nBwyaPQBl6HP1DLNGRIups9LLu=
a4VsoarxeD0Q5c5EzzTZzSxRY39vwp0gv33z2hCGCUijGL3OmcXkO167L0mE0WPBfMOvYAoA8pW=
TPNhIQtCXUawyvlHHeyP5Pk7rr7vPWRIIbYuQCVbkF8D5DQtN8Dk8hbmJ7AJT279nLoJYEWe9Mo=
8xd3yT0ahWJqgMIAxn9vK4yO1ZtrseUrFHEkk-3D
** New Capture the Fracture Partnership aims for 25 Percent Reduction in th=
e Incidence of Hip and Vertebral Fractures due to Osteoporosis by 2025
------------------------------------------------------------
=C2=B7 International Osteoporosis Foundation Announces First of Its Kind Pa=
rtnership with University of Oxford, UCB and Amgen to combat global public =
health burden of osteoporosis^1
=C2=B7 Hip and vertebral fractures are costly for society and can be life-a=
ltering for patients^2,3
BRUSSELS, Belgium (16th June, 2020): UCB (Euronext Brussels: UCB) and Amgen=
(NASDAQ: AMGN) today announced a collaboration with the International Oste=
oporosis Foundation (IOF) to support its Capture the Fracture^=C2=AE progra=
m to reduce hip and vertebral fractures by 25% by 2025. Currently, it is es=
timated that more than 200 million people worldwide suffer from osteoporosi=
s^4, resulting in an osteoporosis-related fracture every three seconds.^5
Osteoporosis is a serious chronic condition that weakens bone over time, ma=
king them thinner and more likely to break,^5 but there are steps patients =
and healthcare providers can take to reduce fracture risk.^1 Capture the Fr=
acture, an IOF initiative, now supported by Amgen and UCB in collaboration =
with the University of Oxford, is a global program that helps to proactivel=
y implement post-fracture care (PFC) coordination programs in hospitals and=
healthcare systems to help patients prevent subsequent fractures due to os=
teoporosis. Even after an osteoporosis-related fracture approximately 80% o=
f individuals at high risk are still not identified or treated.^6
=E2=80=9COsteoporosis remains a global concern, resulting in 8.9 million fr=
actures in a single year^3 and a previous fracture increases the risk of an=
other osteoporosis-related fracture by 86 percent.^7 Early intervention thr=
ough improved post-fracture identification, diagnosis and treatment in appr=
opriate patients can help improve outcomes while also lessening the cost bu=
rden on healthcare systems^5,=E2=80=9D said Darryl Sleep, M.D., senior vice=
president of Global Medical and chief medical officer at Amgen. =E2=80=9CS=
upporting Capture the Fracture represents our proactive approach to care de=
signed to predict and help prevent potentially life-altering fractures befo=
re they happen.=E2=80=9D
=E2=80=9CWe are currently witnessing a significant disease burden. As the w=
orldwide aging population steadily increases, it has never been more import=
ant to address the impact that osteoporosis and associated fractures can ha=
ve on individuals,=E2=80=9D said Professor Cyrus Cooper, president of the I=
nternational Osteoporosis Foundation and Professor of Musculoskeletal Scien=
ce at the University of Oxford.
=E2=80=9CWe know post-fracture co-ordinated care implementation is the most=
effective^8 and efficient intervention to close the secondary fracture pre=
vention gap, so I=E2=80=99m delighted that Amgen, UCB and the University of=
Oxford will support our Capture the Fracture program as we embark on a mis=
sion to improve outcomes for patients,=E2=80=9D said IOF chief executive of=
ficer, Dr. Philippe Halbout.
Osteoporosis is treated by multiple specialties, underscoring the need for =
coordinated care to support patients with the disease. At the core of the C=
apture the Fracture model is a care coordinator who can help patients with =
an osteoporosis-related fracture be identified, screened, diagnosed and app=
ropriately treated to reduce their future fracture risk. Post-fracture care=
coordination programs have been shown to improve diagnosis and treatment r=
ates.^8,9 This partnership aims to double the 390 existing Capture the Frac=
ture programs by the end of 2022, and will focus on key regions including A=
sia Pacific, Latin America, the Middle East, and Europe.
=E2=80=9CThe introduction of the post-fracture care model is recognized as =
a progressive milestone in the management of osteoporosis and osteoporotic =
fractures and remains a profound example of what good looks like in coordin=
ation of care among multiple disconnected players,=E2=80=9D said Professor =
Dr. Iris Loew-Friedrich, chief medical officer and executive vice president=
, UCB. =E2=80=9CCollaboration and cross learning are necessary if we are to=
face the challenges of the future and find a way to lessen the burden face=
d by healthcare systems and people living with osteoporosis. This global pa=
rtnership supports UCB's ambition of connected healthcare, finding ways to =
deliver more for the patient and transforming the lives of people with seve=
re diseases.=E2=80=9D
This partnership also welcomes collaboration from existing fracture prevent=
ion coalitions on international, national and regional levels to drive frac=
ture prevention policy change and prioritization. Additional elements of th=
e partnership include developing and implementing efficiencies and best pra=
ctice sharing across PFC program sites, creating a digital tool that docume=
nts and communicates PFC effectiveness, and providing virtual and in-person=
mentorship and learning opportunities for healthcare providers.
=E2=80=9CCapture the Fracture is an incredible opportunity to take the acad=
emic skills and expertise from the university to deliver real improvements =
in patient care for osteoporosis,=E2=80=9D said Dr. Kassim Javaid, Associat=
e Professor, the Nuffield Department of Orthopaedics, Rheumatology and Musc=
uloskeletal Sciences (NDORMS), University of Oxford. Dr. Javaid, along with=
Dr. Rafael Pinedo-Villanueva, will be responsible for the mentorship progr=
am and for developing a benefits calculator for the PFC program. =E2=80=9CW=
e hope that through this program millions of lives will be changed, and we =
look forward to working with national and international colleagues to deliv=
er this vision.=E2=80=9D =C2=A0
For more information about Capture the Fracture, please visit https://u7061=
146.ct.sendgrid.net/ls/click?upn=3DTeZUXWpUv-2B6TCY38pVLo9qUf3L3FF27bxkm-2F=
NLvitdTZylHYzWELTHtMUWEg9A89ydnW_xDPID0vOuylFAU8fv4e60wei4JxqEGBdVWu7KiDwjI=
3b8sYN46DL86bSl0KxvPs6EFaZqddW-2FBZlGB52Zlf-2FOeoCOG9ekocVj-2F2X9c9g1wYOvrt=
M6DlJeULeIaUcHdhgXOVk1wLTP3tkYficVDrAo3nBwyaPQBl6HP1DLNGRIups9LLua4VsoarxeD=
0Q5c5EzzTZzSxRY39vwp0gv33z2ig2soC93Tu-2FJB9S5u6I494cMr-2B1kj5akKu5VW8gODIen=
-2BRgH1-2FwOpTJdthudGcW3YMaIWywwLbGn4O2WMfE5GST6Yeqn4xvVZWj5rMa-2F4TtcvOQ0T=
sbRNJQpS5irT0PdTHdht9Wbj-2F8RQ3d9SN45OA-3D (https://u7061146.ct.sendgrid.ne=
t/ls/click?upn=3DTeZUXWpUv-2B6TCY38pVLo9qUf3L3FF27bxkm-2FNLvitdQHhG5QHvFQJu=
94CFxdFmNiaTfe_xDPID0vOuylFAU8fv4e60wei4JxqEGBdVWu7KiDwjI3b8sYN46DL86bSl0Kx=
vPs6EFaZqddW-2FBZlGB52Zlf-2FOeoCOG9ekocVj-2F2X9c9g1wYOvrtM6DlJeULeIaUcHdhgX=
OVk1wLTP3tkYficVDrAo3nBwyaPQBl6HP1DLNGRIups9LLua4VsoarxeD0Q5c5EzzTZzSxRY39v=
wp0gv33z2ihNmveUCTBXwvgcX-2FsjREXeAqkrX4B8WXNn1JRUybZcI7v74fdmzbqxm11kKeluY=
ytCMhfXlTPihfDsXqXnf61DAsa2Xpwhtkci3D-2FU8jhI-2Fv5GWQ4RMzSVYrx6HFEAHI6JpNAy=
lmPTMwdaVNw5ZtI-3D .=C2=A0
About UCB
UCB, Brussels, Belgium (www.ucb.com) is a global biopharmaceutical company =
focused on the discovery and development of innovative medicines and soluti=
ons to transform the lives of people living with severe diseases of the imm=
une system or of the central nervous system. With 7 500 people in approxima=
tely 40 countries, the company generated revenue of =E2=82=AC 4.9 billion i=
n 2019. UCB is listed on Euronext Brussels (symbol: UCB). Follow us on Twit=
ter: @UCB_news (https://u7061146.ct.sendgrid.net/ls/click?upn=3D4tNED-2FM8i=
DZJQyQ53jATUe2lj6oWHHXtZgwkiNwqDdXnOq5rqXLFB-2FdXpffw9GyGTe7T_xDPID0vOuylFA=
U8fv4e60wei4JxqEGBdVWu7KiDwjI3b8sYN46DL86bSl0KxvPs6EFaZqddW-2FBZlGB52Zlf-2F=
OeoCOG9ekocVj-2F2X9c9g1wYOvrtM6DlJeULeIaUcHdhgXOVk1wLTP3tkYficVDrAo3nBwyaPQ=
Bl6HP1DLNGRIups9LLua4VsoarxeD0Q5c5EzzTZzSxRY39vwp0gv33z2v-2ButxT-2Bq80DJyGU=
8ZGG76Q5zbrO8mGefRnYPWe3axTqXWpXyrha1E-2FUPq-2B8yG0DIjss5s48W1fqPVFoJErCV-2=
B1wCmIrShmTe-2BUxDiPZIYMBj-2FI0M4dH26YhP6cEh5z69YHbsKZeielzJMiGxzQse0g-3D
About Amgen
Amgen is committed to unlocking the potential of biology for patients suffe=
ring from serious illnesses by discovering, developing, manufacturing and d=
elivering innovative human therapeutics. This approach begins by using tool=
s like advanced human genetics to unravel the complexities of disease and u=
nderstand the fundamentals of human biology.
Amgen focuses on areas of high unmet medical need and leverages its experti=
se to strive for solutions that improve health outcomes and dramatically im=
prove people's lives. A biotechnology pioneer since 1980, Amgen has grown t=
o be one of the world's leading independent biotechnology companies, has re=
ached millions of patients around the world and is developing a pipeline of=
medicines with breakaway potential.
For more information, visit www.amgen.com (https://u7061146.ct.sendgrid.net=
/ls/click?upn=3DTeZUXWpUv-2B6TCY38pVLo9pz6KCxeXhEjlt-2BBs9dbF7o-3D7uxo_xDPI=
D0vOuylFAU8fv4e60wei4JxqEGBdVWu7KiDwjI3b8sYN46DL86bSl0KxvPs6EFaZqddW-2FBZlG=
B52Zlf-2FOeoCOG9ekocVj-2F2X9c9g1wYOvrtM6DlJeULeIaUcHdhgXOVk1wLTP3tkYficVDrA=
o3nBwyaPQBl6HP1DLNGRIups9LLua4VsoarxeD0Q5c5EzzTZzSxRY39vwp0gv33z2rTTrlpa6mW=
SQCrLM8VlVIG02yz9Df6V2qIb2XG9nRoUp4JeHjq5qVti7bQ2WFczk2YtOKJdpZlXW9lAxr68ub=
xJ3INODx1h-2FDpBNRdEFZMTJ2tqWsRFvqIq1jFtFXMyzmbQG5z0SmRtuwuYK-2BPwvVI-3D an=
d follow us on www.twitter.com/amgen (https://u7061146.ct.sendgrid.net/ls/c=
lick?upn=3DTeZUXWpUv-2B6TCY38pVLo9pra2icLBqlEoqemsTLgKvbdUoyoa9gNgsI1xu6-2B=
uRexuKer_xDPID0vOuylFAU8fv4e60wei4JxqEGBdVWu7KiDwjI3b8sYN46DL86bSl0KxvPs6EF=
aZqddW-2FBZlGB52Zlf-2FOeoCOG9ekocVj-2F2X9c9g1wYOvrtM6DlJeULeIaUcHdhgXOVk1wL=
TP3tkYficVDrAo3nBwyaPQBl6HP1DLNGRIups9LLua4VsoarxeD0Q5c5EzzTZzSxRY39vwp0gv3=
3z2rzsFlLoiIykoKIib2S2byywFeSY3X536n6cryQYnSlTx0OKn-2FivOEZ9w8HiiweV5QcuI1v=
epsBS7IIgusmTM5a6OW8WnKerrpkFXxt48qA-2BzMwZ4-2BE6-2BX4JAzy2RqRWb78QwKWOsEKs=
giWo1vofTS0-3D .
About International Osteoporosis Foundation
The International Osteoporosis Foundation (IOF) is a registered not-for-pro=
fit, non-governmental foundation based in Switzerland. =C2=A0IOF has been g=
ranted Roster Consultative Status with the Economic and Social Council of t=
he United Nations.
IOF functions as a global alliance of patient societies, research organizat=
ions, healthcare professionals and international companies working to promo=
te bone, muscle and joint health. www.iofbonehealth.org (https://u7061146.c=
t.sendgrid.net/ls/click?upn=3DTeZUXWpUv-2B6TCY38pVLo9h4bsj0O2glpZM95aXDR2tj=
nATLq2hJ-2F1qxAbFNh6U7hFcvE_xDPID0vOuylFAU8fv4e60wei4JxqEGBdVWu7KiDwjI3b8sY=
N46DL86bSl0KxvPs6EFaZqddW-2FBZlGB52Zlf-2FOeoCOG9ekocVj-2F2X9c9g1wYOvrtM6DlJ=
eULeIaUcHdhgXOVk1wLTP3tkYficVDrAo3nBwyaPQBl6HP1DLNGRIups9LLua4VsoarxeD0Q5c5=
EzzTZzSxRY39vwp0gv33z2sep4yZ5DZ2Ek1KAJ4EfR0NFTBRVpmiJZpBEXXJ-2BEfuc-2FGTQ2X=
m4O320LS8CHtUh5o5Xz0aYoFnSMUfQ-2BWJwu3jjfJwA4ovzfxFHEtFKXwbCKyu-2FTb8rTehy-=
2F5d7csJbksep6is9JqlmTv-2BuP0sQEo8-3D =C2=A0
About University of Oxford
Oxford University has been placed number 1 in the Times Higher Education Wo=
rld University Rankings for the fourth year running, and at the heart of th=
is success is our groundbreaking research and innovation.
Oxford is world-famous for research excellence and home to some of the most=
talented people from across the globe. Our work helps the lives of million=
s, solving real-world problems through a huge network of partnerships and c=
ollaborations. The breadth and interdisciplinary nature of our research spa=
rks imaginative and inventive insights and solutions.
About The Nuffield Department of Orthopaedics, Rheumatology and Musculoskel=
etal Sciences (NDORMS)
The Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal S=
ciences (NDORMS) is a multi-disciplinary department focusing on discovering=
the causes of musculoskeletal and inflammatory conditions to deliver excel=
lent and innovative care that improves people=E2=80=99s quality of life. Th=
e largest European academic department in its field, NDORMS is part of the =
Medical Sciences Division of the University of Oxford and is a rapidly grow=
ing community of more than 500 orthopaedic surgeons, rheumatologists and sc=
ientists all working in the field of musculoskeletal disorders.=C2=A0
The research work of the department takes place in several locations across=
the Nuffield Orthopaedic Centre, namely the Botnar Research Centre, the Ke=
nnedy Institute of Rheumatology, and the Kadoorie Centre. The co-location w=
ith NHS services puts the department in an excellent position with basic re=
searchers working alongside clinicians. This substantially improves researc=
h capacity, improving access for researchers to patients, and facilitating =
the interaction between clinicians and scientists that is essential for suc=
cessful medical research. www.ndorms.ox.ac.uk=C2=A0 (https://u7061146.ct.se=
ndgrid.net/ls/click?upn=3DTeZUXWpUv-2B6TCY38pVLo9nWtZDqTmfr3U95QAuxlGnhVBO-=
2BiL5oWVHAxejxpH-2BdBIIY6_xDPID0vOuylFAU8fv4e60wei4JxqEGBdVWu7KiDwjI3b8sYN4=
6DL86bSl0KxvPs6EFaZqddW-2FBZlGB52Zlf-2FOeoCOG9ekocVj-2F2X9c9g1wYOvrtM6DlJeU=
LeIaUcHdhgXOVk1wLTP3tkYficVDrAo3nBwyaPQBl6HP1DLNGRIups9LLua4VsoarxeD0Q5c5Ez=
zTZzSxRY39vwp0gv33z2pTtDwH0KTvqvYiN8Sr0FjhLZoU7V8IWOZ19KEwWfp612M9jCxkxIfMv=
4xVKfGhBBvIyHOgimsblPPs-2B6ICzadzbwRhgZWR6G73Bh4HqOZnpkpPyqB-2BvFzBZTaRbnZ1=
Yy6PmwwRkWNU-2FKkKf4UDpC5A-3D
CONTACT: UCB
Scott Fleming, Bone Communications, UCB, T +44 7702777378, scott.fleming@uc=
b.com
CONTACT: Amgen, Thousand Oaks
Jessica Akopyan, 805-447-0974 (media)=C2=A0
Trish Rowland, 805-447-5631 (media)
CONTACT: International Osteoporosis Foundation=C2=A0
Laura Misteli, Communications Editor, T +41 0788571777, lmisteli@iofbonehea=
lth.org=C2=A0
CONTACT: University of Oxford
Josie Eade, Communications Officer, josie.eade@ndorms.ox.ac.uk=C2=A0
References
1. International Osteoporosis Foundation. IOF Compendium of Osteoporosis 2n=
d Edition. https://u7061146.ct.sendgrid.net/ls/click?upn=3DTeZUXWpUv-2B6TCY=
38pVLo9sJO4tVPGSp90Wl6WPmfSYyjM5cp8ppVqcAEIsVC-2FERWFu0odxcRMghNKSx7sSvP-2B=
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Iups9LLua4VsoarxeD0Q5c5EzzTZzSxRY39vwp0gv33z2tNYbLj9mc-2Ba2-2F-2BR97CknChS1=
-2BPV-2BN2319G7x-2BXbJsBqtv4SG1Nmhms-2FeGBMcsJ8UKvH8Q6S3M9DQN-2F8oa2VcIVnhd=
stJiV6NxvXMHsue-2BH75BPvPX6zcJqxtsq4mLPrABIrU7ooGw6B004U6oTSo9c-3D Accessed=
March 11, 2020.=C2=A0
2. Burge R, Dawson-Hughes B, Solomon DH, et alWong JB, King A, Tosteson A. =
Incidence and economic burden of osteoporosis-related fractures in the Unit=
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global campaign to break the fragility fracture cycle (October 2012). https=
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1wLTP3tkYficVDrAo3nBwyaPQBl6HP1DLNGRIups9LLua4VsoarxeD0Q5c5EzzTZzSxRY39vwp0=
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FYm-2FLCDNi8IiD2LxWZ8XF1gPGuc6wEg6AUTcL-2F-2F37Zg2wi5uMv-2BDI3whT-2B5HKmu7X=
h2SlUay-2BQ0exOH-2FJ-2BT02FDsNx4-3D Accessed March 11, 2020.
6. Nguyen TV, Center JR, Eisman JA. Osteoporosis: underrated, underdiagnose=
d and undertreated. Med J Aust. 2004;180:S18-S22.
7. Kanis JA, De LAet C, Delmas P, Garnero P, Johansson H, Johnell O, Kriger=
H, McCloskey EV, Mellstrom D, Melton LJ III, Od=C3=A9n A, Pols H, Reeve J,=
Silman A, Tenenhouse A. A meta-analysis of previous fracture and fracture =
risk. Bone 2004 35;375-82
8. Akesson et al. Capture the Fracture: a Best Practice Framework and globa=
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9. Ganda et al. Models of care for the secondary prevention of osteoporotic=
fractures: a systematic review and meta-analysis Osteoporos Int (2013) 24:=
393=E2=80=93406
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