Abivax announces presentation of four abstracts for obefazimod in ulcerative colitis and sponsorship of scientific symposium at the 19th Congress of European Crohn’s and Colitis Organization (ECCO)

PARIS, France, February 13, 2024, 8:30 a.m. CET – Abivax SA (Euronext Paris & Nasdaq: ABVX) (“Abivax” or the “Company”), a clinical-stage biotechnology company focused on developing therapeutics that harness the body’s natural regulatory mechanisms to stabilize the immune response in patients with chronic inflammatory diseases, today announced that four scientific abstracts on its lead drug candidate, obefazimod for the treatment of moderately to severely active ulcerative colitis (UC), will be presented during the 19^th Congress of the European Crohn’s and Colitis Organisation (ECCO) on February 21-24, 2024, in Stockholm, Sweden.

“We are delighted that all four submitted abstracts have been accepted for presentations at ECCO. We look forward to scientific exchange with the IBD community at ECCO,” said Sheldon Sloan, M.D., M. Bioethics, Chief Medical Officer of Abivax. “The ECCO Congress provides an excellent platform to present new data and to continue raising awareness of the unique mechanism of action of obefazimod, which available data indicate exerts its anti-inflammatory activity by stabilizing the immune response in patients with ulcerative colitis.”

Abivax has also sponsored a scientific symposium titled “Expanding the Armamentarium: Emerging MOAs for Treating Ulcerative Colitis” featuring speakers Prof. Bruce E. Sands, M.D., M.S. (United States), and Prof. Raja Atreya, M.D. (Germany), on February 23, 2024, at 7:15-8:15 a.m. CET in room A12.

The Symposium will be broadcasted live and is accessible publicly here. No ECCO registration is required to view the broadcast.

For more information visit the Abivax booth at the ECCO exhibitor hall (booth #15) or see congress details at the ECCO website.

Obefazimod data to be presented:

About Obefazimod

Obefazimod, Abivax’s lead investigational drug candidate, is an oral small molecule that was demonstrated to enhance the expression of a single microRNA, miR-124. Phase 2 clinical trials in patients with UC have generated positive topline data, resulting in the initiation of a pivotal global Phase 3 clinical trial program (ABTECT Program), with first patients enrolled in the United States in October 2022. Initiation of a Phase 2b clinical trial in Crohn’s disease is expected in Q3 2024, and exploration of potential combination therapy opportunities in UC is ongoing.

About Abivax

Abivax is a clinical-stage biotechnology company focused on developing therapeutics that harness the body’s natural regulatory mechanisms to stabilize the immune response in patients with chronic inflammatory diseases. Based in France and the United States, Abivax’s lead drug candidate, obefazimod (ABX464), is in Phase 3 clinical trials for the treatment of moderately to severely active ulcerative colitis. More information on the Company is available at www.abivax.com. Follow us on LinkedIn and on X, formerly Twitter, @ABIVAX.

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